Zoloft� sertraline hydrochloride tablets and oral concentrate
Kazrajin/ October 2, 2012/ Aleve & Naproxen
The concomitant use of sertraline hydrochloride with MAOIs is contraindicated.
What is sertraline?
The effectiveness of sertraline hydrochloride for the treatment of OCD was demonstrated in a week, multicenter, placebo-controlled, parallel group study in a pediatric outpatient population ages 6 to 17 Study OCD It may decrease fear, anxietyunwanted thoughts, and the number of panic attacks.
Increased risk of suicidal thinking and behavior in children, adolescents, and young adults; monitor for clinical worsening or unusual changes. Metabolism and nutrition disorders — hyponatremia, hyperglycemia Musculoskeletal and connective tissue disorders — trismus.
Nauseadizzinessdrowsiness, dry mouthloss of appetiteincreased sweatingdiarrheaupset stomachor trouble sleeping may occur. In general, dose selection for an elderly patient should be conservative, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Post hoc exploratory analyses revealed a statistically significant difference between ZOLOFT and placebo on the CAPS, IES and CGI in women, regardless of baseline diagnosis of comorbid major depressive disorder, but essentially no effect in the relatively smaller number of men in these studies.
Sertraline hydrochloride should be prescribed with caution in patients with a seizure disorder. Some conditions may become worse when this drug is suddenly stopped.
The background risk of major birth defects and miscarriage for the indicated population are unknown. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Some products that may interact with this drug include: Physicians should note that in a prospective longitudinal study of women with a history of major depression who were euthymic in the condiv of antidepressant therapy at the beginning of pregnancy, women who discontinued antidepressant medication during pregnancy were more likely to experience a relapse of major depression than women who continued antidepressant medication.
Call your healthcare provider if you have eye pain, changes in your vision, or swelling or redness in or around the eye. Study outcome was assessed by the:. In over pediatric patients treated with ZOLOFT, the overall profile of adverse events was generally similar to that seen in adult studies.
Inform patients of the increased risk of bleeding associated with the concomitant use of sertraline hydrochloride and antiplatelet agents and anticoagulants. These findings are based on post-marketing reports.
Inform pregnant women that sertraline hydrochloride may cause withdrawal symptoms in the newborn or persistent pulmonary hypertension of the newborn PPHN [See Use in Specific Populations 8.
In a placebo-controlled trial in normal volunteers, the administration of two doses of sertraline hydrochloride did not significantly alter steady-state lithium levels or the renal clearance of lithium [See Drug Interactions 7. In addition, at least 14 days must elapse after stopping sertraline hydrochloride oral solution before starting an MAOI antidepressant [See Contraindications 4Warnings and Precautions 5. ZOLOFT can cause sleepiness or may affect your ability to make decisions, think clearly, or react quickly.
Hepatobiliary disorders — severe liver events including hepatitis, jaundice, liver failure with some fatal outcomespancreatitis. Overview Side Effects Dosage More. Do not start new medicines without first checking with your healthcare provider.
If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.
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